GEL-MA INX

Gelatin-Methacrylamide, first developed in our lab in 2000, has emerged as one of the gold standards in tissue engineering and biofabrication worldwide.

GEL-MA INX© is a gelatin-based ink exhibiting ideal extracellular matrix-mimicking properties as it is derived from natural collagen, the main component of the natural extra-cellular matrix. Gel-MA derived from gelatin type B shows ideal properties as it is cell-interactive due to the presence of RGD motifs in its backbone. It is biodegradable, can be remodeled by cells, and can be printed by taking advantage of its temperature-dependent physical gelation behavior. It becomes physiologically stable after photo-crosslinking, thereby forming a non-soluble network. As a result of all these beneficial properties Gel-MA has emerged to be one of the gold standards in the field of tissue engineering and biofabrication.

Product is provided as a clear hydrogel in a prefilled cartridge of 3 ml.

Printer requirements: Heatable printhead (25 - 30 °C) with nozzle insulator and cooled printbed (10 °C)

PUBLICATIONS:

Agten H. et al. "In vitro and in vivo evaluation of 3D Constructs engineered with human iPSC-derived chondrocytes in gelatin methacryloyl hydrogel" - Biotechnology and Bioengineering, 119(10)  (https://doi.org/10.1002/bit.28168)

Arslan A. et al. "Increasing the Microfabrication Performance of Synthetic Hydrogel Precursors through Molecular Design" - Biomacromolecules 2021, 22, 12, 4919 - 4932 (https://doi.org/10.1021/acs.biomac.1c00704)